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Purpose:
To describe five young patients, who presented with myopic choroidal neovascularization (mCNV) as the preliminary sign of punctate inner choroidopathy (PIC)
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Methods:
Retrospective review
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Results:
Five myopic patients (2 females, 3 males), with a mean age of 27.6±9.91 years, initially presented with mCNV in one eye. Mean refractive error was -9.20±3.17 diopters. Mean
time interval between mCNV development and appearance of PIC was 11.02±9.67 months.
Mean LogMAR best-corrected visual acuity (BCVA) at presentation with mCNV was 0.35±0.48. At PIC diagnosis, mean LogMAR BCVA was 0.11±0.12 and it was 0.07±0.05 at the last follow-up (p= 0.059). mCNV was treated with intravitreal bevacizumab injection in all cases. Corticosteroids were instituted for the treatment of PIC in all patients. A steroid-sparing agent was used in three patients and adalimumab was additionally used in two patients. Mean follow-up time was 23.4±14.62 months. -
Conclusions:
mCNV was the initial presenting sign of PIC in five patients. It appeared in the absence of conspicuous clinical and imaging findings in either eye until the emergence of the
classic PIC lesions. mCNV may indicate occult inflammation heralding the development of inflammatory chorioretinopathies. Close follow-up and a high index of suspicion is essential for the timely diagnosis and management.